He was the main antagonist of several story arcs over the years before being demoted to disciple of Apocalypse. He is also the archenemy of the Summer Family in general, particularly Cyclops, being personally responsible for manipulating and orchestrating numerous tragedies in the former's life, as well as his creation, Madelyne Pryor. He is a powerful mutant supervillain that is often depicted as being the right-hand of Apocalypse, although they tend use each other only for their own ends and eventually went on their separate ways.Ī brilliant geneticist, he is obsessed with evolution and evolving humanity, as well as creating what he views to be the perfect mutant, with his schemes to do so frequently bringing him into conflict with the X-Men. Nathaniel Essex, better known as Mister Sinister, is a major antagonist in Marvel Comics particularly as a foe for the X-Men.
It takes more than bullets - or a harlot's kiss - to kill Nathaniel Essex.
